Why was this course developed?
The Certificate in Advanced Chromatographic Techniques was developed based on an analysis of the importance of the pharmaceutical and related industries in Ireland and within the South-East region and also using information generated from the Wales Ireland Network for Scientific Skills (WINSS) Scientific Survey from a large number of pharmaceutical/biotechnology, medical device and food companies. One of the outputs from this survey indicated that 45% of the companies surveyed require training in HPLC techniques while 37% require GC training. Recognising this demand, the Certificate in Advanced Chromatographic Techniques was devised to provide advanced level training and address this skills deficit.
This course was developed to provide the student with an advanced understanding of the theory, practices and instrumentation associated with chromatographic separation techniques. The focus is primarily on High Performance Liquid Chromatography (HPLC) and Gas Chromatography (GC), Ion Chromatography IC and reverse-phase bioseparations. The interfacing of hyphenated techniques involving Mass Spectrometry (MS), such as LC-MS and GC-MS, is also covered.
The student will be exposed to state-of-the-art developments in associated instrumentation, and learn to competently operate, calibrate and qualify associated laboratory instrumentation. The student will be exposed to the application of advanced chromatographic techniques in a wide range of industrial environments focusing mainly, but not exclusively, on applications in the pharmaceutical and biopharmaceutical industries. This will enable them to select an appropriate separation technique for a given analysis in a range of industrial environments. The student will also learn to resolve sample preparation and method development issues for the chromatographic separation of samples in complex matrices.
What are the learning outcomes?
On successful completion of this module, a student will be able to:
•Explain the principles, practices and instrumentation associated with advanced chromatography, as well as interfacing of hyphenated techniques involving mass-spectrometry such as LC-MS and GC-MS.
•Select an appropriate separation technique for a given analysis in a range of industrial environments.
•Resolve sample preparation issues concerned with GC, HPLC, ion chromatography and reverse-phase bioseparations.
•Resolve method development issues concerned with GC, HPLC, ion chromatography and reverse-phase bioseparations.
•Competently operate, calibrate and qualify associated laboratory instrumentation for pharmaceutical and biopharmaceutical sample analyses.
•Critically appraise separation science literature and identify future trends in this area.