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Advanced Drug Formulation Science

Description
Why was this course developed?
The South East region has a significant Life Sciences cluster, with c. 7,500 people employed and c. 1,700 new jobs projected over the next 3-5 years. There is a skills shortage at higher levels (Level 8-9) for expert scientists and technicians to perform formulation and other R&D activities. In response, companies are having to identify people within their organisations that can develop these skills, and are looking to work with WIT to put in place the training to upskill these key staff. The forecast growth in the sector in the South East is expected to make this shortage more acute and is creating an imperative to increase the numbers of people that are trained in these high-skill areas.

The Future Skills Needs of the Biopharma industry in Ireland report published in 2016 highlighted a need for advanced scientific skills at L8/L9. The National Skills Bulletin 2016 highlighted a shortage of Analytical Development Chemists, Formulation Scientists, R&D Scientists, and QC Analysts. The skills shortage in advanced formulation applies to approximately 15 companies (pharmaceutical companies in or moving to the region), who collectively require a skills pool of 40-50 formulation scientists. Allowing for promotions, retirements and people moving in and out of the region, it is estimated that there is a need to train at least ten people per annum to the level required.

What are the learning outcomes?
On successful completion of this module, a student will be able to:
•Appraise the principles of pharmaceutical/biopharmaceutical pre-formulation with respect to the overall design and development of drug delivery systems.

•Evaluate how the physicochemical properties of drug molecules and excipients influence the choice of drug dosage form and subsequent formulation and manufacturing procedures.

•Propose a formulation design and method of manufacture taking into account the physicochemical properties of drug molecules and excipients.

•Establish method development strategies involved in lyophilisation, spray drying and aerosol drug formulation.

•Produce a protocol for the stability testing of a pharmaceutical product

Entry requirements

The Certificate in Advanced Drug Formulation Science is aimed at participants who are employed within the pharmaceutical and medtech companies, and who wish to upskill or seek employment in the formulation departments of such organisations.

Advanced Drug Formulation Science Entry Requirements
•Applicants for entry to this Certificate course should hold a bachelor's degree at honours level minimum 2.2 (Level 8) in an appropriate subject area or equivalent qualification.

•In addition, in order to fully appreciate the industrial impact of the content of this programme, it has been deemed necessary to have a minimum of two years relevant industrial experience.

•Applicants whose first language is not English must submit evidence of competency in English, please see WIT's English Language Requirements for details.

Duration

4 months part-time.

How is this course delivered?
•The Certificate in Advanced Drug Formulation Science programme is taught using a block approach on a part-time basis to facilitate students in full-time employment.

•Since this course is also offered as one module of the two year MSc in Analytical Science with Quality Management programme, Certificate in Advanced Drug Formulation Science is only offered once every two years. The course will next run in March 2019, subject to sufficient student numbers.

•Over the duration of the programme, students will be required to attend WIT for 8 days. The delivery dates for the 2018-19 academic year are as follows:

◦Lectures Friday and Saturday 01 & 02 March 2019

◦Lectures Friday and Saturday 22 & 23 March 2019

◦Lectures Friday and Saturday 05 & 06 April 2019

◦Laboratory Practical Week beginning Monday 29 April 2019

•In line with current education practice, the programme is designed to be learner-focussed and the teaching and learning strategy will involve the exposure of students to a wide range of learning experiences. They will be encouraged to reflect on their own learning experiences in lecture and practical sessions and to become self-directed learners.

•Lectures will be used to introduce the concepts involved in Formulation Science as well as an in-depth investigation into the area. The inclusion of a significant practical element in the modules is carefully aligned with theory content. The practical element is scheduled to run after theory content has been delivered. Specific practical training will be given on formulation techniques by both lecturing staff and researchers in the Pharmaceutical & Molecular Biotechnology Research Centre (PMBRC).

•Each student will have an individual project which will be based in WIT or possibly a host company (subject to approval by the company and WIT). The student will have to prepare a written report in advance of their laboratory work. This report will entail a high degree of self-directed learning and will involve research on a specific drug and dosage form. The student will be required to demonstrate a sound understanding of the formulation methodology with justification for the choice of excipients and manufacturing process. Additionally, a project plan will be submitted in advance of the practical with justification for the experimental design. The report for the practical will involve the student critically analysing the results of the experiments and drawing scientific conclusions.

•Continuous assessment will be carried out throughout the course of the programme.

Number of credits

10

Careers or further progression

Opportunities
This course places a strong emphasis on the professional development of the graduate and is aimed at students already working in an industrial environment. Such a qualification will enable and facilitate career progression for graduates in the region.

This programme can be taken as a stand-alone Certificate worth 10 credits at level 9, or if the student wishes, they can use these credits towards the 60 credit Postgraduate Diploma in Analytical Science with Quality Management (WD 519) or the 90 credit MSc in Analytical Science with Quality Management (WD 520).

Further enquiries

Course Leader
Dr. Richie Ryan
Pharmaceutical Science Lecturer
Tel: 51 845509
Email: RJRYAN@wit.ie

Comment

Campus: Cork Road

Application date

The closing date to apply for this programme is Thursday 31 January 2019.

Course fee

€1700

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